By Reha Erzurumlu, William Guido, Zoltan Molnar

This quantity presents an replace at the multitude of technical and experimental techniques in figuring out the improvement and plasticity of the mammalian sensory thalamus and neocortex. the point of interest is on visible and somatosensory thalamus and neocortex in rodents and carnivores, and practical imaging stories in constructing and getting older human neocortex. It additional offers an artificial theoretical framework for destiny reviews.

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45 46 Tomomi Shimogori and Elizabeth A. Grove Figure 4 VB axon trajectory is shown in FGF8 early and late augmented thalamocortical section. A, VB axons follow the area identity in subplate to penetrate into cortex (arrow) and arborize in layer 6a and layer 4 in register. B, In the early FGF8 overexpressed brain, area identity in subplate and cortex are both shifted. Hence, VB axon entry into cortex and arbors in layer 6a and layer 4 are all in line. C, In the late FGF8 overexpressed brain, area identity of subplate is remain as same as control brain.

Highlighting is used to identify molecules whose expression is regulated by Pax6. Families of molecule enclosed by boxes are those which include members that are prime candidates for being regulated in the thalamus, directly or indirectly, by Pax6. Many molecules inside the cell might have their expression affected by Pax6, but evidence is lacking at present: for simplicity, the pathways that may link these molecules are not drawn. Many of the families of molecule indicated are very large. Literature on which this diagram is based is cited in Song and Poo (2001) and in the text.

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