By Jason H. Moore
The sector of genetics is speedily evolving, and new scientific breakthroughs are taking place due to advances in wisdom won from genetics reasearch. This thematic quantity of Advances in Genetics appears at Computational tools for Genetics of advanced qualities. the sector of genetics is quickly evolving, and new clinical breakthroughs are taking place because of advances in wisdom won from genetics reasearch. This thematic quantity of Advances in Genetics seems at Computational tools for Genetics of advanced features.
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Additional info for Computational Methods for Genetics of Complex Traits
2005). Finding associations in dense genetic maps: A genetic algorithm approach. Hum. Hered. 60, 97–108. Clark, T. , and Griffiths, R. C. (2007). Bayesian logistic regression using a perfect phylogeny. Biostatistics 8, 32–52. Clark, T. , and Griffiths, R. C. (2008). An evolutionary algorithm to find associations in dense genetic maps. IEEE Trans. Evol. Comp. 12, 297–306. Cordell, H. , Barratt, B. , and Clayton, D. G. (2004). Case/pseudocontrol analysis in genetic association studies: A unified framework for detection of genotype and haplotype associations, genegene and gene-environment interactions, and parent-of-origin effects.
2006). Fast “coalescent” simulation. BMC Genet. 7, 16. Moore, J. , Hahn, L. , Ritchie, M. , Thornton, T. , and White, B. (2004). Routine discovery of high-order epistasis models for computational studies in human genetics. Appl. Soft Comput. 4, 79–86. Motsinger, A. , Ritchie, M. , and Reif, D. M. (2007). Novel methods for detecting epistasis in pharmacogenomics studies. Pharmacogenomics 1229–1241. , and Sing, C. (2001). A combinatorial partitioning approach to identify multilocus genotypic partitions that predict quantitative trait variation.
1982). The coalescent. Stochastic Processes Appl. 13, 235–248. , LeBlanc, M. , and Hsu, L. (2001). Sequence analysis using logic regression. Genet. Epidemiol. 21(Suppl. 1), S626–S631. , and Chen, Y. (2008). Generating samples for association studies based on HapMap data. BMC Bioinform. 9, 44. , and Li, M. (2008). GWAsimulator: A rapid whole-genome simulation program. Bioinformatics 24, 140–142. , and Abecasis, G. R. (2007). GENOME: A rapid coalescent-based whole genome simulator. Bioinformatics 23, 1565–1567.