By Robert Plomin, John C. Defries, Ian W. Craig, Peter McGuffin

The second one writer is with the Univ. of Colorado, Boulder. provides a dialogue of genetic learn on habit and makes a speciality of cognitive talents, character, psychopathology, and psychopharmacology. Written for psychology, psychiatry, behavioral, biomedical, and organic sciences execs.

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Extra info for Behavioral Genetics in the Postgenomic Era

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The power to do so by genome screening depends not only on the number of cases and controls available for study and the validity of the diagnosis but also, critically, on the proximity of any genetic marker to the functional locus. An Alternative to Whole Genome Scans for QTLs Given the uncertainties concerning the distribution of linkage disequilibrium across the genome and its likely variation in different populations, does the information emerging from genome studies provide a way forward to more efficient screening for QTLs.

Annual Review of Genomics and Human Genetics, 1 , 329360. , & Ronaghi, M. (1997). Detection of single-base changes using a bioluminometric primer extension assay. Analytical Biochemistry, 244, 367-373. , et al. (2001). A genomewide scan of 1842 DNA markers for allelic associations with general cognitive ability: A five-stage design using DNA pooling and extreme selected groups. Behavior Genetics, 31, 497-509. Pritchard, J. , & Rosenberg, N. A. (1999). Use of unlinked genetic markers to detect population stratification in association studies.

Williams, N. , & Owen, M. J. Selective DNA pooling using automated technology: A rapid technique for allelic association studies i n quantitative traits and complex diseases. Psychiatry Genetics, 5(Suppl. l ) , 50. MOLECULAR GENETICS 39 Fan, J. , Halushka, M. , et al. Parallel genotyping of human SNPs using generic high-density oligonucleotide tag arrays. Genome Research, 10, 853-860. Faraone, S. ,Doyle, A. , & Biederman, J . (2001). Meta-analysis of the association between the 7-repeat allele of the dopamine d(4) receptor gene and attention deficit hyperactivity disorder.

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