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37,38'53 The crossbridges in which the motor domain is not at the rigor position on actin and the lever arm is up at a high angle may represent weak contacts between myosin and actin at the beginning of a power stroke that realign on actin to reach a strong binding position. Or, they may be nonstereospecific contacts that do not evolve into force producing interactions. The range of rebuilt SI models in HST was ordered into a hypothetical sequence compatible with a continuously attached, progressive -12 nm power stroke comprising an angular range of > 100° to 45°.

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